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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDC42BPA
All Species:
17.27
Human Site:
Y790
Identified Species:
42.22
UniProt:
Q5VT25
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5VT25
NP_003598.2
1732
197307
Y790
L
D
K
L
T
T
L
Y
E
N
L
S
I
H
N
Chimpanzee
Pan troglodytes
XP_510180
1757
198525
V833
N
E
K
L
C
S
F
V
D
K
L
T
A
Q
N
Rhesus Macaque
Macaca mulatta
XP_001088134
1781
202813
Y790
L
D
K
L
T
T
L
Y
E
N
L
S
I
H
N
Dog
Lupus familis
XP_851425
1732
197292
Y790
L
D
K
L
T
T
L
Y
E
N
V
S
M
R
N
Cat
Felis silvestris
Mouse
Mus musculus
Q3UU96
1719
195518
Y790
L
D
K
L
T
S
L
Y
E
S
L
S
L
R
N
Rat
Rattus norvegicus
O54874
1732
197045
Y790
L
D
K
L
T
S
L
Y
E
S
L
S
L
R
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513203
1718
195063
F790
V
D
K
L
T
T
M
F
E
R
L
S
V
N
N
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W1B0
1637
186706
K771
I
Q
W
V
S
D
E
K
D
A
R
G
Y
L
Q
Honey Bee
Apis mellifera
XP_395596
1741
197744
I793
E
A
Q
I
T
E
I
I
Q
W
V
S
D
E
K
Nematode Worm
Caenorhab. elegans
P92199
1173
135756
A311
I
I
K
K
F
L
S
A
A
P
D
R
L
G
R
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
59.5
95.6
96.8
N.A.
95.3
95.9
N.A.
88.3
N.A.
N.A.
N.A.
N.A.
44.3
50.4
24.4
N.A.
Protein Similarity:
100
76.3
96.2
99
N.A.
97.8
98.3
N.A.
94.5
N.A.
N.A.
N.A.
N.A.
63.6
67.8
42.3
N.A.
P-Site Identity:
100
26.6
100
80
N.A.
73.3
73.3
N.A.
60
N.A.
N.A.
N.A.
N.A.
0
13.3
6.6
N.A.
P-Site Similarity:
100
53.3
100
93.3
N.A.
93.3
93.3
N.A.
93.3
N.A.
N.A.
N.A.
N.A.
26.6
46.6
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
0
0
10
10
10
0
0
10
0
0
% A
% Cys:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
60
0
0
0
10
0
0
20
0
10
0
10
0
0
% D
% Glu:
10
10
0
0
0
10
10
0
60
0
0
0
0
10
0
% E
% Phe:
0
0
0
0
10
0
10
10
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
10
0
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
20
0
% H
% Ile:
20
10
0
10
0
0
10
10
0
0
0
0
20
0
0
% I
% Lys:
0
0
80
10
0
0
0
10
0
10
0
0
0
0
10
% K
% Leu:
50
0
0
70
0
10
50
0
0
0
60
0
30
10
0
% L
% Met:
0
0
0
0
0
0
10
0
0
0
0
0
10
0
0
% M
% Asn:
10
0
0
0
0
0
0
0
0
30
0
0
0
10
70
% N
% Pro:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% P
% Gln:
0
10
10
0
0
0
0
0
10
0
0
0
0
10
10
% Q
% Arg:
0
0
0
0
0
0
0
0
0
10
10
10
0
30
10
% R
% Ser:
0
0
0
0
10
30
10
0
0
20
0
70
0
0
0
% S
% Thr:
0
0
0
0
70
40
0
0
0
0
0
10
0
0
0
% T
% Val:
10
0
0
10
0
0
0
10
0
0
20
0
10
0
0
% V
% Trp:
0
0
10
0
0
0
0
0
0
10
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
50
0
0
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _